Colimax 0.6mg Tablet | View Uses, Dosage, Interaction, Price
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Home Medicines Gout Colimax 0.6mg Tablet 10pcs
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Colimax 0.6mg Tablet 10pcs

Generic: Colchicine

Type: Tablet

Pack Size: 10 Pcs

Colimax 0.6mg Tablet is used to prevent gout.


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Discount Price: ৳ 55.8
MRP: ৳ 60 7% Off

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✅ Description:

Colchicine-Antigout agents

  • Short-term management of gout attacks in adults
  • Prevention of gout recurrence
  • Management of Familial Mediterranean Fever (FMF), including fever attacks and amyloidosis

Colimax 0.6mg Tablet is used to treat and prevent gout attacks and manage symptoms of FMF, a genetic disorder causing recurrent fevers and inflammation.

Colchicine reduces uric acid crystal buildup in joints, decreasing swelling and pain in gout. In FMF, it decreases amyloid protein production, alleviating pain in the abdomen, chest, or joints.

  • Inform your doctor of any allergies, blood disorders, heart, kidney, or liver disease.
  • Not recommended for patients with severe liver or kidney disease.
  • Avoid use during pregnancy for gout management; use caution in FMF if necessary.
  • Women of childbearing potential should use contraception during and for 3 months post-treatment.
  • Not recommended for children under 18 for gout; consult a doctor for FMF management in children under 5 and adolescents 10-18 years old.

Safety Advices


Alcohol
UNSAFE

Avoid consuming alcohol while taking Colimax 0.6mg Tablet. Consult your doctor before taking this medication.


Pregnancy
CONSULT YOUR DOCTOR

Colimax 0.6mg Tablet is not recommended for use in pregnant women for gout management. It should only be used in cases of familial Mediterranean fever (FMF) if necessary. Women of childbearing potential should use effective contraception during and for at least three months after discontinuing Colimax 0.6mg Tablet for gout management. Consult your doctor before taking this medication.


Breastfeeding
CONSULT YOUR DOCTOR

Colimax 0.6mg Tablet is not recommended for breastfeeding women when used for gout management. For FMF, it should be used with caution and only if clearly necessary. Consult your doctor before using this medication while breastfeeding.


Driving
CAUTION

Colimax 0.6mg Tablet may cause drowsiness and dizziness, which can impair your ability to drive or operate machinery. Consult your doctor before taking this medication.


Kidney
CONSULT YOUR DOCTOR

Colimax 0.6mg Tablet should be used with caution in patients with kidney problems, and careful monitoring by your doctor is required. It is not recommended for use in patients with severe renal impairment. Consult your doctor for advice before taking this medication.


Liver
CONSULT YOUR DOCTOR

Colimax 0.6mg Tablet should be used with caution in patients with liver problems and requires careful monitoring by your doctor. It is not recommended for use in patients with severely impaired liver disease. Consult your doctor for advice before taking this medication.

Similar Products

✔️ Uses of Colimax 0.6mg Tablet
  • Gout
✔️ How does Colimax 0.6mg Tablet work?

Colimax reduces inflammation which causes pain, swelling, and other symptoms of gout.

✔️ Side Effects of Colimax 0.6mg Tablet
  • Blood dyscrasias: Myelosuppression, leukopenia, granulocytopenia, thrombocytopenia, and aplastic anemia.
  • Diarrhea and pharyngolaryngeal pain may occur.
✔️ Quick Suggestions:
  • Colchicine is used for the treatment and prevention of gout.
  • It interacts with many different medicines. Inform your doctor about all the medications that you are taking.
  • Inform your doctor if you have serious nausea, vomiting, diarrhea, or if you have tingling in your fingers or toe.
  • It can lower your body's ability to make new blood cells. Inform your doctor if you have frequent bleeding, bruising, fevers, or if you are always tired.
  • Do not take Colchicine if you have severe liver disease or kidney disease, or if you are pregnant or breastfeeding.
✔️ Colimax is used for:
  • Treating acute gout flares.
  • Managing Familial Mediterranean fever (FMF) in adults and children aged 4 years and older.
✔️ Pharmacology

Colimax is FDA-approved to prevent and treat sudden severe gout attacks. In gout, uric acid crystals deposit in joints, prompting white blood cells to attempt to engulf them, releasing lactic acid and pro-inflammatory enzymes. This leads to the characteristic pain and swelling of gout. Colimax inhibits white blood cell migration to inflamed areas, reducing pain and inflammation.

An acute gout attack results from an inflammatory reaction to monosodium urate crystals deposited in joint tissue, exacerbated by more crystal accumulation. Leukocytes migrate to these sites, trying to engulf the crystals, releasing lactic acid and pro-inflammatory enzymes. This causes inflammation with severe pain, redness, and swelling. Colchicine inhibits the phagocytosis of uric acid by leukocytes and reduces lactic acid production, disrupting the cycle of urate crystal deposition and the inflammatory response, and alleviating the acute attack of gout.

Colchicine is orally absorbed, reaching a mean peak concentration (Cmax) of 2.5 ng/mL in 1 to 2 hours after a single dose on an empty stomach. The mean apparent volume of distribution is approximately 5 to 8 L/kg. Colchicine binds low to serum protein (39 ± 5%), primarily to albumin. It is metabolized by CYP3A4 into 2-O-demethylcolchicine and 3-O-demethylcolchicine. Plasma levels of these metabolites are minimal. Following multiple oral doses (0.6 mg twice daily), the mean elimination half-life is 26.6 to 31.2 hours.

✔️ Dosage & Administration of Colimax 0.6mg Tablet

Acute Gouty Arthritis:

  • First dose: 1 to 1.2 mg (two 0.5 mg or two 0.6 mg tablets) every 2 hours until pain and inflammation subside.
  • The total amount needed to control pain and inflammation during an attack typically ranges from 4 to 8 mg.
  • Pain and swelling usually reduce within 12 hours and disappear within 24 to 48 hours.
  • A three-day interval between courses is advised to minimize cumulative toxicity.

Prophylaxis During Intercritical Periods:

  • To reduce frequency and severity, colchicine may be administered continuously.
  • For patients with less than one attack per year, the usual dose is 0.5 or 0.6 mg per day, three or four days a week.
  • For more than one attack per year, the usual dose is 0.5 or 0.6 mg daily.
  • Severe cases may require two or three 0.5 mg or 0.6 mg tablets daily.

Prophylaxis Against Attacks in Patients Undergoing Surgery:

  • For patients with gout, even minor surgery can trigger an attack.
  • Administer one 0.5 mg or 0.6 mg tablet three times daily for three days before and three days after surgery.

Pediatric Use: Gout is rare in pediatric patients, and the safety and effectiveness of Colimax in this population have not been established.

✔️ Interaction

Co-administration with P-gp and/or CYP3A4 inhibitors (e.g., clarithromycin or cyclosporine) alters Colimax concentration.

✔️ Contraindications

Not recommended for patients with renal or hepatic impairment when used with P-gp or strong CYP3A4 inhibitors (e.g., clarithromycin or cyclosporine).

✔️ Pregnancy & Lactation
  • Pregnancy Category C: No adequate and well-controlled studies in pregnant women.
  • Excreted into human milk: Exercise caution when administered to nursing women.
✔️ Precautions & Warnings
  • Elderly: Use with caution due to increased sensitivity to side effects.
  • Gastrointestinal Disease: Exercise caution as the drug may exacerbate symptoms.
  • Cardiac, Renal, and Hepatic Impairment: Use with caution. The drug is not recommended for patients with severe impairment in these organs.
  • Prolonged Therapy: Not recommended due to potential cumulative toxicity.
  • Lactation: Colchicine enters breast milk. Use with caution during breastfeeding. The American Academy of Pediatrics Committee states that colchicine is "compatible" with nursing.
✔️ Storage Conditions:

Store below 30°C, protected from light and moisture. Keep out of reach of children.

Frequently Asked Questions (FAQ)

Don’t stop your medication abruptly. Consult your doctor before stopping any medicine, and never attempt to do it on your own

Colimax 0.6mg Tablet may affect your blood sugar level. If you are a patient suffering from diabetes, take Colchicine as recommended by your doctor

If you forget to take Colimax 0.6mg Tablet, take another dose as soon as you remember. If it is almost time for your next dose, do not take the missed dose at all and continue as per your prescribed dosing regime. Consult your doctor if you are not sure about the missed dose.

Colimax 0.6mg Tablet is not recommended for use to manage gout in children and adolescents (below 18 years of age).
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Check our pricing section for Colimax 0.6mg Tablet 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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